Fig. 6. Treatment with triptolide at 20 μg·kg⁻¹·d⁻¹ after chronic cerebral hypoperfusion had no hepatotoxic or nephrotoxic effects.

Liver function was evaluated by measuring the levels of (a) aspartate aminotransferase (AST) and (b) alanine aminotransferase (ALT), and kidney function was evaluated by measuring the levels of (c) total albumin (ALB), (d) creatinine and (e) blood urea nitrogen (BUN) in serum at 28 d after rUCCAO in mice administered with triptolide at a dosage of 20 μg·kg⁻¹·d⁻¹ (TP20). n = 6–7 mice per group from at least three independent behavior experiments.