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. 2021 Dec 21;9:751785. doi: 10.3389/fcell.2021.751785

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Copyright © 2021 Peng, Sha, Liu, Chen, Xu, Xie, Deng and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Inhibition of angiogenesis by Cabo alleviates LL37-induced rosacea-like phenotype. (A) Representative photographs of dorsal skin of mice from different groups. (B,C) Quantitative analysis of the redness area (B) and score of erythema (C) in dorsal skin of mice. (D,E) H&E staining and quantitative analysis of the number of cell infiltration. Scale bar: 50 μm. (F,G) Immunofluorescence staining with CD31 and quantitation of CD31⁺ vessels in skin tissues from four groups. Scale bar: 50 μm. Data represent mean ± SEM from three independent experiments. Statistical significance was determined by One-way ANOVA (B,C,E,G). *p < 0.05 and **p < 0.01.