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. 2022 Jan 4;2022(1):CD013345. doi: 10.1002/14651858.CD013345.pub2

An 2017.

Methods Study design: randomised clinical trial
Study duration: January 2013 to January 2015
Duration of follow‐up: 2 years
Setting: hospital
Participants Number of participants: 98
Inclusion criteria: diagnosed as HCC; single or huge tumour; no PVTT; no history of other tumours
Age (mean ± SD, range): TACE + MWA: 51.3 ± 2.9 years, 24‐78 years; TACE alone: 50.3 ± 2.6 years, 23‐78 years
Male (n/total): TACE + MWA: 40/49; TACE alone: 39/49
Interventions TACE + MWA group (n = 49):
TACE: TACE comprised of hepatic arterial infusion chemotherapy and hepatic artery embolisation Chemotherapeutic drugs: adriamycin 40 mg and fluorouracil 1 g
MWA: the interval between TACE and MWA was 2 weeks. Output power of 50‐60W. Time of 10‐20 minutes per ablation application
Control group (n = 49):
TACE comprised of hepatic arterial infusion chemotherapy and hepatic artery embolisation Chemotherapeutic drugs: adriamycin 40 mg and fluorouracil 1 g
Outcomes Tumour response: measured by contrast‐enhanced CT; at 4 months after treatment
1‐year and 2‐year survival rates: measured at 1 year and 2 years after treatment
Adverse events
Notes Country of study: China
Source of funding: none
There was insufficient information available to satisfactorily determine the method of randomisation and the study data could not be verified. We have attempted to contact the study authors for more information, but so far, we have not been successful in doing this.