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. 2022 Jan 4;2022(1):CD013345. doi: 10.1002/14651858.CD013345.pub2

He 2016.

Methods Study design: Randomised clinical trial
Study duration: March 2015 to December 2015
Duration of follow‐up: 2 years
Setting: Hospital
Participants Inclusion criteria: Diagnosed as HCC by pathology or imaging examination; AFP > 400 μg/L; liver function of Child‐Pugh Class A or B; the number of tumours ≤ 2
Exclusion criteria: With portal vein tumour thrombus and extrahepatic metastasis
Age (mean): TACE + MWA: 52.6 years; TACE alone: 52.9 years
Male (n/total): TACE + MWA: 25/32; TACE alone: 22/28
Tumour diameter (mean): .TACE + MWA: 8.2 cm; TACE alone: 7.9 cm
Child‐Pugh Class (patients):
Class A: TACE + MWA: 13; TACE alone: 11
Class B: TACE + MWA: 19; TACE alone: 17
Interventions TACE + MWA group (n = 32):
TACE: Chemotherapeutic drugs: epirubicin 30‐50 mg and oxaliplatin 200‐150 mg
MWA: CT‐guided MWA. Output power of 55‐60 W. The ablation time of per application was 5‐10 minutes.
TACE group (n = 28):
Chemotherapeutic drugs: epirubicin 30‐50 mg and oxaliplatin 200‐150 mg
Outcomes Serum level of AFP
Tumour response: measured by contrast‐enhanced CT or MRI at 1 month after treatment
Adverse events
1‐ and 2‐year survival rates
Notes Country of study: China
Source of funding: None
There was insufficient information available to satisfactorily determine the method of randomisation and the study data could not be verified. We have attempted to contact the study authors for more information, but so far, we have not been successful in doing this.