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. 2022 Jan 4;2022(1):CD013345. doi: 10.1002/14651858.CD013345.pub2

Lin 2017.

Methods Study design: Randomised clinical trial
Study duration: February 2016 to January 2017
Duration of follow‐up: 3 months
Setting: Hospital
Participants Inclusion criteria: No serious diseases in other organs; tumour numbers < 3; no tumour thrombus in inferior vena cava or portal vein; no extrahepatic metastasis
Age (mean ± SD, range): TACE + RFA: 50.1 ± 2.5 years, 34‐68 years; TACE: 49.2 ± 2.3 years, 33‐67 years
Male (n/total): TACE + RFA: 22/30; TACE alone: 21/30
Child‐Pugh Class (patients):
Class A: TACE + RFA: 22; TACE: 21
Class B: TACE + RFA: 5; TACE: 6
Class C: TACE + RFA: 3; TACE: 3
Interventions TACE + RFA group (n = 30):
TACE: Chemotherapeutic drugs: theprubicin 50 mg, mitomycin 10 mg, and cisplatin 50 mg
RFA: The interval between TACE and RFA was 2 weeks. Output power of 200 W. Total treatment time of 10‐30 minutes
TACE group (n = 30):
Chemotherapeutic drugs: theprubicin 50 mg, mitomycin 10 mg, and cisplatin 50 mg
Outcomes Tumour necrosis: measured by DSA or CT
Tumour recurrence
Notes Funding source: None
Conducted in China
There was insufficient information available to satisfactorily determine the method of randomisation and the study data could not be verified. We have attempted to contact the study authors for more information, but so far, we have not been successful in doing this.