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. 2022 Jan 4;2022(1):CD013345. doi: 10.1002/14651858.CD013345.pub2

Liu 2016a.

Methods Study design: Randomised clinical trial
Study duration: January 2012 to September 2013
Duration of follow‐up: 2 years
Setting: Hospital
Participants Inclusion criteria: Tumour diameter > 5 cm; tumour numbers ≤ 4; liver function of Child‐Pugh Class A and B; willing to sign a written informed consent document
Exclusion criteria: Not suitable for TACE or MWA; with history of liver function or liver transplantation
Age (mean ± SD, range): TACE + MWA: 58.74 ± 7.06 years, 35‐81 years; TACE alone: 58.26 ± 7.31 years, 34‐79 years
Male (n/total): TACE + MWA: 43/62; TACE alone: 45/62
Interventions TACE + MWA group (n = 62):
TACE: Chemotherapeutic drugs: cisplatin 40‐60 mg and 5‐fluorouracil 0.75‐1 g
MWA: The interval between TACE and RFA was 2‐4 weeks. Multiple sessions of MWA were performed with an interval of 2 weeks.
TACE group (n = 62):
Chemotherapeutic drugs: cisplatin 40‐60 mg and 5‐fluorouracil 0.75‐1 g
Outcomes Tumour response: based on WHO criteria; measured at 4 weeks after treatment
Survival rates
Notes Country of study: China
Source of funding: None
There was insufficient information available to satisfactorily determine the method of randomisation and the study data could not be verified. We have attempted to contact the study authors for more information, but so far, we have not been successful in doing this.