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. 2022 Jan 4;2022(1):CD013345. doi: 10.1002/14651858.CD013345.pub2

Xu 2016.

Methods Study design: Randomised clinical trial
Study duration: December 2010 to July 2012
Duration of follow‐up: 3 years
Setting: Hospital
Participants Age (mean ± SD): TACE + RFA: 52.9 ± 5.4 years; TACE alone: 53.4 ± 6.8 years
Male (n/total): TACE + RFA: 28/38; TACE alone: 27/34
Child‐Pugh Class (patients):
Class A: TACE + RFA: 20; TACE: 19
Class B: TACE + RFA: 18; TACE: 15
Interventions TACE + RFA group (n = 38):
TACE: Chemotherapeutic drugs: 5‐fluorouracil, theprubicin, and epirubicin
RFA: The interval between TACE and RFA was 2 weeks. Output power of 50‐100 W
TACE group (n = 34):
Chemotherapeutic drugs: 5‐fluorouracil, theprubicin, and epirubicin
Outcomes Serum level of AFP
Liver function
Tumour response, measured by contrast‐enhanced CT or MRI; measured at 3 months after treatment
1‐, 2‐, and 3‐year survival rates
Notes Country of study: China
Source of funding: Qinhuangdao Science and Develoment Funding
There was insufficient information available to satisfactorily determine the method of randomisation and the study data could not be verified. We have attempted to contact the study authors for more information, but so far, we have not been successful in doing this.