Skip to main content
. 2022 Jan 4;2022(1):CD013345. doi: 10.1002/14651858.CD013345.pub2

Zhang 2013.

Methods Study design: Randomised clinical trial
Study duration: March 2009 to September 2011
Duration of follow‐up: 35 months
Setting: Hospital
Participants Inclusion criteria: Diagnosed as HCC by liver biopsy; tumour maximal diameter of 5‐10 cm; with liver function of Child‐Pugh Class A or B; unsuitable for resection or unwilling to accept surgery; with no history of treatments on HCC
Age (mean ± SD): TACE + MWA: 52.1 ± 1.64 years; TACE alone: 55.57 ± 1.76 years
Male (n/total): TACE + MWA: 48/60; TACE alone: 33/42
Tumour diameter (mean ± SD): TACE + MWA: 7.8 ± 1.37 cm; TACE: 7.34 ± 1.23 cm
Child‐Pugh Class (patients):
Class A: TACE + MWA: 42; TACE: 25
Class B: TACE + MWA: 18; TACE: 17
Interventions TACE + MWA group (n = 60):
TACE: Chemotherapeutic drugs: adriamycin 30‐50 mg. Multiple sessions of TACE were performed, with an interval of 3‐4 weeks.
MWA: Output power of 50‐60 W; 10‐15 minutes per MWA session
TACE group (n = 42):
Chemotherapeutic drugs: adriamycin 30‐50 mg. Multiple sessions of TACE were performed, with an interval of 3‐4 weeks.
Outcomes Serum level of AFP
Tumour response, according to mRECIST criteria, measured at 2 months after treatment
1‐ and 2‐year survival rates
Adverse events
Notes Country of study: China
Source of funding: None
There was insufficient information available to satisfactorily determine the method of randomisation and the study data could not be verified. We have attempted to contact the study authors for more information, but so far, we have not been successful in doing this.