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. 2022 Jan 4;2022(1):CD013345. doi: 10.1002/14651858.CD013345.pub2

Zhang 2017c.

Methods Study design: Randomised clinical trial
Study duration: 2012 to 2014
Duration of follow‐up: 2 years
Setting: Hospital
Participants Inclusion criteria: Diagnosed as HCC by liver biopsy or images; maximal tumour diameter > 5 cm; tumour number ≤ 4; with liver function of Child‐Pugh Class A or B; willing to sign a written informed consent document
Exclusion criteria: With history of liver resection or liver transplantation
Age (mean ± SD): TACE + MWA: 56.9 ± 7.7 years; TACE alone: 58.2 ± 7.3 years
Male (n/total): TACE + MWA: 21/30; TACE alone: 23/30
Interventions TACE + MWA group (n = 30):
TACE: Chemotherapeutic drugs: 5‐fluorouracil 0.075‐1 g and cisplatin 40‐60 mg
MWA: The interval between TACE and RFA was 2‐4 weeks. Multiple sessions of MWA were performed, with an interval of 2 weeks.
TACE group (n = 30): Chemotherapeutic drugs: 5‐fluorouracil 0.075‐1 g and cisplatin 40‐60 mg
Outcomes Tumour response, classified as complete response, partial response, stable disease, and progression, measured at 4 weeks after treatment
1‐ and 2‐year survival rates
Adverse events
Notes Country of study: China
Source of funding: None
There was insufficient information available to satisfactorily determine the method of randomisation and the study data could not be verified. We have attempted to contact the study authors for more information, but so far, we have not been successful in doing this.