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. 2021 Dec 21;12:796590. doi: 10.3389/fphar.2021.796590

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Copyright © 2021 Li, Hou, Wang, Dai, Zhang, Tang, Dong, Yan, Wang, Li and Cao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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DG improved liver and tissue steatosis in mice fed with high fat diet. (A) Serum ALT and AST in each group. (B) Serum TC and TG in each group. (C) Serum level of LPS in each group. (D) Pathological examination of eWAT, iBAT and liver by H&E staining in each group (scale bar: 50 μm). Values were denoted as mean ± SEM (n = 5). *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001. Abbreviations: DG, diammonium glycyrrhizinate. ALT, alanine aminotransferase. AST, aspartate aminotransferase. TC, total cholesterol. TG, total triglyceride. LPS, lipopolysaccharide. eWAT, white adipose tissue of the epididymis. iBAT, interscapular brown adipose tissue.