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. 2021 Dec 21;12:758049. doi: 10.3389/fphar.2021.758049

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Copyright © 2021 Zeng, Yi, Su, Ye, Sun, Zhou, Lu, Shi and Tian.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Key phytochemicals of CR in treating IS. (A) CR main phytochemicals target-IS target network. Red nodes represent the main phytochemicals in CR, and red numbers below these nodes represent the number of CR targets against IS. Green circular nodes represent 85 common targets between the CR and IS. (B) Venn plot showing the number of overlapping potential targets among the three key ingredients. (C) Enriched GO biologic process for top three key phytochemicals -related targets. Numbers above bars are the number of targets enriched in terms.