Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Apr 9;20:100080. doi: 10.1016/j.mcpro.2021.100080

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 The Authors. Published by Elsevier Inc on behalf of American Society for Biochemistry and Molecular Biology.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Fig. 3 — Application of mixed and BigLib multi-HLA spectral libraries for matching immunopeptidomics DIA data. DIA data of JY, OD5P, and RA957 samples were matched against the mixed library comprising immunopeptidomics data from six different biological samples (A). The number of peptides identified in each of the DIA measurements and the number of peptides included in the mixed library are reported. Deconvolution of the consensus binding motifs of JY (B), OD5P (C), and RA957 (D) DIA immunopeptidomics samples with MixMHCp 2.1 and manual annotation of motifs. The number of peptides and the HLA restriction assigned to each motif are reported. DIA data of JY, OD5P, and RA957 samples were matched against the BigLib library comprising immunopeptidomics data from 40 different biological samples (E). The number of peptides identified in each of the DIA measurements and the number of peptides included in the mixed library are reported. Deconvolution of the consensus binding motifs of JY (F), OD5P (G), and RA957 (H) DIA immunopeptidomics samples as described above. DIA, data-independent acquisition; HLA, human leukocyte antigen.