Table 1.
Small molecules | Cells expressing polyGP‐GFP | Cells expressing AUG‐RFP | polyGP‐GFP intensity | AUG‐RFP intensity | Number of cells |
---|---|---|---|---|---|
DMSO | −0.06 | −0.2 | 0.3 | −0.12 | −0.2 |
Erysolin (ERY) | −3.5 | −0.2 | −1.34 | −0.7 | −1.1 |
Forskolin (FSK) | 20.3 | −2.4 | 27 | −0.8 | 0.05 |
Geldanamycin (GELD) | −5 | 1.6 | 0.002 | 3 | −2.6 |
Helenin (HLN) | −1.05 | −0.7 | −2.8 | −1.1 | −1.3 |
Spironolactone (SPL) | −0.5 | 0.7 | −2.3 | 0.6 | −0.9 |
Mean of compounds from four biological replicates. All the compounds were added after 3h of reverse co‐transfection and used at the final concentration of 5 µM for approximately 30 h. Mean of DMSO from 64 biological replicates (32 replicates per each 384‐well plate). Data are reported as Z‐score values.
The entire list of small molecules used is reported in Dataset EV1.