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. 2021 Nov 18;41(1):e105026. doi: 10.15252/embj.2020105026

Table 1.

List of the small molecules selected from the confirmatory screening.

Small molecules Cells expressing polyGP‐GFP Cells expressing AUG‐RFP polyGP‐GFP intensity AUG‐RFP intensity Number of cells
DMSO −0.06 −0.2 0.3 −0.12 −0.2
Erysolin (ERY) −3.5 −0.2 −1.34 −0.7 −1.1
Forskolin (FSK) 20.3 −2.4 27 −0.8 0.05
Geldanamycin (GELD) −5 1.6 0.002 3 −2.6
Helenin (HLN) −1.05 −0.7 −2.8 −1.1 −1.3
Spironolactone (SPL) −0.5 0.7 −2.3 0.6 −0.9

Mean of compounds from four biological replicates. All the compounds were added after 3h of reverse co‐transfection and used at the final concentration of 5 µM for approximately 30 h. Mean of DMSO from 64 biological replicates (32 replicates per each 384‐well plate). Data are reported as Z‐score values.

The entire list of small molecules used is reported in Dataset EV1.