Table 3. Characteristics of CSU cases with positive anti-TPO IgG or positive anti-TG IgG.
| Parameter | Anti-TPO IgG | Anti-TG IgG | |||||
|---|---|---|---|---|---|---|---|
| Positive (n = 292) | Negative (n = 808) | P value | Positive (n = 334) | Negative (n = 766) | P value | ||
| Age (yr) | 38.4 ± 11.6 | 39.1 ± 11.4 | 0.392 | 39.2 ± 11.7 | 38.8 ± 11.3 | 0.575 | |
| Female | 218 (74.7) | 548 (67.8) | 0.031 | 250 (74.9) | 516 (67.4) | 0.015 | |
| Disease duration (mon) | 10.5 (3–36) | 12 (3–36) | 0.710 | 12 (3–36) | 10 (3–36) | 0.568 | |
| UASday | 4.4 ± 1.3 | 4.4 ± 1.3 | 0.416 | 4.4 ± 1.3 | 4.4 ± 1.3 | 0.733 | |
| Reduced TSH | 2 (0.68) | 3 (0.37) | 0.613 | 1 (0.30) | 4 (0.52) | 0.999 | |
| Elevated TSH | 7 (2.40) | 9 (1.11) | 0.153 | 5 (1.50) | 11 (1.44) | 0.999 | |
| tIgE (IU/mL) | 77.6 (35.5–153.8) | 109.8 (53.1–186.2) | < 0.001 | 99.4 (43.0–170.2) | 105.2 (47.3–179.2) | 0.229 | |
| > 100 IU/mL | 128 (43.8) | 423 (52.4) | 0.014 | 165 (49.4) | 386 (50.4) | 0.793 | |
| > 150 IU/mL | 77 (26.4) | 280 (34.7) | 0.011 | 103 (30.8) | 254 (33.2) | 0.484 | |
| < 40 IU/mL | 87 (29.8) | 156 (19.3) | < 0.001 | 81 (24.3) | 162 (21.1) | 0.269 | |
| Positive sIgE | 83 (28.4) | 180 (22.3) | 0.038 | 81 (24.3) | 182 (23.8) | 0.878 | |
| Positive inhalant sIgE | 43 (14.7) | 106 (13.1) | 0.486 | 43 (12.9) | 106 (13.8) | 0.702 | |
| Positive food sIgE | 57 (19.5) | 119 (14.7) | 0.062 | 55 (16.5) | 121 (15.8) | 0.789 | |
| Antihistamine-refractory cases | 95 (34.1) | 87 (13.9) | < 0.001 | 76 (25.1) | 106 (17.5) | 0.008 | |
Values are presented as mean ± SD, median (interquartile range) or number (%).
The P values in bold are statistically significant at level P < 0.05.
CSU, chronic spontaneous urticaria; TPO, thyroid peroxidase; TG, thyroglobulin; Ig, immunoglobulin; UASday, urticaria activity score for 1 day; TSH, thyroid stimulating hormone, or thyrotropin; tIgE, total IgE; sIgE, specific IgE.