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. Author manuscript; available in PMC: 2022 Jul 13.
Published in final edited form as: Prog Neuropsychopharmacol Biol Psychiatry. 2021 Feb 4;109:110259. doi: 10.1016/j.pnpbp.2021.110259

Table 3.

depicts fecal levels of acetic acid, propionic acid, isobutyric acid, butyric acid, 2-methyl butyric acid, isovaleric acid, valeric acid, isocaproic acid, and caproic acid in RTT and WT rats at p35, p105, and p196. There were no significant differences in RTT and WT samples at any developmental timepoint measured. Values depicted are log2 transformed data values.

SCFA Age RTT
Average
pmol/mg
RTT
STE
pmol/mg
WT
Average
pmol/mg
WT
STE
pmol/mg
p-value
acetic acid p35 14.75 0.27 14.68 0.02 n.s.
p105 14.95 0.20 14.41 0.21 n.s.
p196 14.40 0.28 14.88 0.18 n.s.
propionic acid p35 12.55 0.22 12.49 0.07 n.s.
p105 12.78 0.19 12.13 0.32 n.s.
p196 12.12 0.23 12.66 0.15 n.s.
iso-butyric acid p35 7.54 0.43 7.96 0.33 n.s.
p105 8.15 0.40 7.50 0.54 n.s.
p196 7.55 0.40 8.38 0.23 n.s.
butyric acid p35 11.30 0.49 11.73 0.13 n.s.
p105 11.92 0.46 11.02 0.39 n.s.
p196 11.72 0.39 12.24 0.29 n.s.
2-methyl butyric acid p35 6.10 0.62 6.70 0.48 n.s.
p105 6.65 0.56 6.31 0.59 n.s.
p196 6.24 0.53 7.29 0.23 n.s.
iso-valeric acid p35 6.46 0.47 7.04 0.40 n.s.
p105 7.09 0.50 6.60 0.58 n.s.
p196 6.39 0.40 7.42 0.24 n.s.
valeric acid p35 7.77 0.66 8.67 0.19 n.s.
p105 8.71 0.48 7.79 0.70 n.s.
p196 8.19 0.37 9.18 0.25 n.s.
iso-caproic acid p35 2.59 0.38 1.68 0.22 n.s.
p105 2.42 0.51 2.03 0.31 n.s.
p196 2.29 0.40 1.91 0.36 n.s.
caproic acid p35 5.59 1.37 5.47 1.09 n.s.
p105 5.28 1.42 3.29 0.70 n.s.
p196 3.00 0.53 3.74 0.70 n.s.