TABLE 2.
bPET Reference Parameters, Lesion-Based Parameters, DTTV Parameters, and First-Order Heterogeneity Parameters
| bPET Parameter | All Patients (n = 91) | Responders (n = 71) | Nonresponders (n = 20) | P* |
|---|---|---|---|---|
| Reference tissue | ||||
| SUVmax liver | 0.49 | |||
| Mean (SD) | 5.7 (2.1) | 5.8 (2.3) | 5.3 (1.6) | |
| Minimum–maximum | 2–13.1 | 3.2–8.2 | 2–13.1 | |
| SUVmax spleen | 0.30 | |||
| Mean (SD) | 13.8 (6.9) | 14.1 (6.9) | 12.6 (6.7) | |
| Minimum–maximum | 4.4–45.8 | 4.4–26.7 | 5–45.8 | |
| Lesion based | ||||
| Mean SUVmax | 0.018 | |||
| Mean (SD) | 38.7 (25.1) | 41.7 (26.8) | 28.2 (14.2) | |
| Minimum–maximum | 11–137.7 | 13.4–77.4 | 11–137.7 | |
| Mean SUVmax T/L | 0.024 | |||
| Mean (SD) | 8.3 (6.4) | 9 (7) | 5.8 (2.9) | |
| Minimum–maximum | 1.4–40.5 | 1.4–40.5 | 2.9–14.6 | |
| Mean SUVmax T/S | 0.13 | |||
| Mean (SD) | 3.5 (2.7) | 3.7 (2.9) | 2.8 (1.8) | |
| Minimum–maximum | 0.2–14.6 | 0.2–14.6 | 1–8.3 | |
| DTTV | ||||
| DTTV liver† | 0.12 | |||
| Mean (SD) | 554.1 (853.8) | 611.5 (921.7) | 350.4 (516.8) | |
| Minimum–maximum | 4.7–4,891.8 | 4.7–4,891.8 | 8.1–2,200.9 | |
| DTTV spleen† | 0.06 | |||
| Mean (SD) | 317.1 (616.3) | 363.9 (677.6) | 150.9 (265.4) | |
| Minimum–maximum | 0–3,825.3 | 0–3,825.3 | 0–1,049.6 | |
| DTTV SUVmax | 0.025 | |||
| Mean (SD) | 62.8 (46.4) | 66.8 (48.4) | 48.4 (36.2) | |
| Minimum–maximum | 15.6–307) | 17.1–307 | 15.6–186.6 | |
| DTTV SUVmean liver | 0.0055 | |||
| Mean (SD) | 15.6 (7.3) | 16.7 (7.7) | 11.6 (3.6) | |
| Minimum–maximum | 5.1–41.4 | 5.8–41.4 | 5.1–19.4 | |
| DTTV SUVmean spleen | 0.06 | |||
| Mean (SD) | 23.5 (10.3) | 24.5 (10.4) | 20 (9.3) | |
| Minimum–maximum | 0–50.4 | 0–50.4 | 7.7–45.3 | |
| Heterogeneity | ||||
| CoV | 0.17 | |||
| Mean (SD) | 0.6 (0.2) | 0.6 (0.2) | 0.6 (0.3) | |
| Minimum–maximum | 0.2–1.6 | 0.3–1.5 | 0.2–1.6 | |
| Skewness | 0.055 | |||
| Mean (SD) | 1.5 (0.8) | 1.4 (0.8) | 1.9 (1.0) | |
| Minimum–maximum | 0.1–4 | 0.1–4 | 0.6–4 | |
| Kurtosis | 0.031 | |||
| Mean (SD) | 6.4 (4.8) | 5.8 (4.1) | 8.6 (6.4) | |
| Minimum–maximum | 1.7–26.7 | 1.7–25.8 | 2.8–26.7 |
*
P value.
†
Measured in cubic centimeters.
DTTV SUVmean liver = SUVmean in segmented volume obtained with liver as threshold; DTTV SUVmean spleen = SUVmean in segmented volume obtained with spleen as threshold; DTTV liver = DTTV obtained with liver as threshold; DTTV spleen = DTTV obtained with spleen as threshold; DTTV SUVmean liver = DTTV SUVmean obtained with liver as threshold; DTTV SUVmean spleen = DTTV SUVmean obtained with spleen as threshold; CoV = coefficient of variation.
Wilcoxon rank sum test P values are shown.