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. 2021 Oct;62(10):1334–1340. doi: 10.2967/jnumed.120.259747

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© 2021 by the Society of Nuclear Medicine and Molecular Imaging.

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FIGURE 1. — ¹⁸F-FDG PET/MRI helps to characterize activity in tonsils and stage patients with lymphoma. (A and B) Axial T2-weighted fat-saturated fast-spin-echo (FSE) image (A) and ¹⁸F-FDG PET image (B) of 15-y-old boy with follicular lymphoma show symmetric morphology and marked ¹⁸F-FDG uptake of both tonsils with reactive hyperplasia. (C and D) Axial T2-weighted FSE image (C) and ¹⁸F-FDG PET image (D) of 4-y-old girl with large B-cell lymphoma demonstrate asymmetric globular enlargement and relatively less intensive ¹⁸F-FDG uptake of left tonsil (arrows). Tonsillectomy revealed large B-cell lymphoma in left tonsil and reactive tissue in right tonsil. Intrinsic uptake in tonsil is more avid than lymphomatous involvement on second patient. Radiologists must be cognizant of this caveat and integrate metabolic and morphologic information to increase diagnostic accuracy.