Fig. 6.

PAKib affected intracellular pathways. The intracellular pathways affected by PAKib were calculated and identified using Cytoscape software. The data with significant changes in phosphosites generated through Perseus was formatted and entered to Cytoscape software where the related network pathways (solid grey lines) were identified, and the extended network pathways (red dotted lines) were also deduced. The red notes represented PAKib-increased phosphosites in related proteins while the green notes the PAKib-decreased phosphosites in related proteins.