Figure 2.

Role of various growth factors and inflammatory mediators in causing progression of DR in pregnancy with diabetes. (TNF-α – tumor necrosis factor, IL-6 and 10 – interleukin-6 and 10, CRP – C-reactive protein, VCAM-1 – vascular endothelial adhesion molecule-1, ICAM-1 – intercellular adhesion molecule-1, ELAM – endothelial leucocyte adhesion molecule, IGF-1 – insulin growth factor-1, IGFBP – insulin growth factor binding protein, FGF – fibroblast growth factor, TGF α and β – transforming growth factor α and β, PEDF – pigment epithelial derived factor)