Figure 7.
Magnitudes and distributions of cell cluster-induced hydrogel deformations and forces. Cell clusters (n = 9) displayed similar trends between (a) shear and (b) normal deformation with spread area, as well as (c) shear vs normal, that was observed for individual cells. (a,b) are normalized to the highest value measured in the individual, single-cell data in the respective category (i.e., shear or normal). Shear and normal data in (c) are normalized to the highest normal deformation measured in individual cells. (d–f) Calculated forces corresponding to (a–c), respectively.