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. Author manuscript; available in PMC: 2022 Nov 15.
Published in final edited form as: J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Oct 19;1185:123000. doi: 10.1016/j.jchromb.2021.123000

Table 4.

Pharmacokinetic parameters of polydatin and resveratrol after oral administration of polydatin (20 mg/kg) to rat (n=4)

Parameters Polydatin Resveratrol
Tmax(h) 0.33 ± 0.11 0.33 ± 0.12
Cmax(μg/L) 0.56 ± 0.14 0.36 ± 0.11
AUC0~t(μg h/L) 0.55 ± 0.16 0.39 ± 0.04
MRT(h) 1.16 ± 0.07 1.82± 0.47
T1/2(h) 1.02± 0.08 1.74 ± 0.58
CL(L/hr/kg) 201.67 ± 54.10 136.7± 3.42
Vz(L/kg) 304.01 ± 68.85 344.3± 114.65