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. 2022 Jan 3;23:17. doi: 10.1186/s12891-021-04917-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Analysis of micro computed tomography. A Represntative CT images of three-dimensional reconstruction in each group (Green: implant; Yellow: new bone formation inside the implant; Gray: calvarium). B Images of coronal section showing new bone formation inside the implant (Rex box: region of interest, ROI). C Three-dimensional reconstruction of the new bone formation in ROI. D-E Quantitative analysis of bone-implant contact (BIC) and bone volume density (BV/TV) in ROI. (Error bars represent SD, ^**P<0.01, control group versus PTH group, n = 6)