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. 2022 Jan 4;4:4. doi: 10.1186/s42238-021-00115-8

Table 2.

Themes in responses to open-ended questions

Theme/subtheme Count
Comparisons between Delta-8 THC and Delta-9 THC 239
 Overall similarity of experience 38
 Delta-8 THC is less intense or potent than Delta-9 THC 38
 Delta-8 THC enables better mental clarity than Delta-9 THC 37
 Delta-8 THC produces less anxiety than Delta-9 THC 28
 Delta-8 THC produces less paranoia than Delta-9 THC 20
 Delta-8 THC has a lower cost than Delta-9 THC 11
 Delta-8 THC is more accessible than Delta-9 THC 7
 Prefers Delta-8 THC 6
 Delta-8 THC has a shorter duration of effect than Delta-9 THC 6
 Delta-8 THC produces less sedation than Delta-9 THC 5
 Can be more active and/or productive with Delta-8 THC 5
 Prefers Delta-9 THC 4
 Delta-8 THC is legal so no risk of arrest, job loss, etc. 3
 Delta-8 THC is harsher on the lungs when inhaled 3
 Delta-8 THC has better social acceptance 3
 Delta-8 THC provides better pain relief 3
 Delta-8 THC stimulated the appetite less than Delta-9 THC 3
 Delta-8 THC generates fewer or no panic attacks 2
 Delta-8 THC provides better relaxation 2
 Delta-8 THC has lesser (unspecified) adverse effects 2
Therapeutic effect or benefit from Delta-8 THC 62
 Relaxation 15
 Pain relief 9
 Anxiety 9
 Sleep aid 6
 Maintaining a positive mood 4
 Post-traumatic stress disorder (PTSD) 3
 Depression 3
 Migraines 2
 Increasing appetite 2
Comments on the study or researchers 33
 Praise for the researchers for conducting a study on Delta-8 22
 Feedback and suggestions on the survey content or features 9
 Criticism of study design 2
Expressions of concern 22
 Concern for continued legal access to Delta-8 THC 17
 Concern for the purity of the product 3
General expressions of praise for Delta-8 THC 19
Substitution of Delta-8 THC for other substances 17
Cannabis and cannabis products containing Delta-9 THC 6
Comparisons between Delta-8 THC and pharmaceutical drugs 11
 Delta-8 THC is better at pain relief 3
Dual use of Delta-8 THC and Delta-9 THC 8
 Delta-8 THC is for working and being active and Delta-9 THC is for fun, relaxation, and recreation 5
Adverse effects of Delta-8 THC 6
 Anxiety (at high doses) 2
 Headache 2
Other comments 25
 Delta-8 THC Edibles or tinctures are more potent than vaping 7
 Building tolerance to Delta-8 THC 3
 Biochemistry of Delta-8 THC 2
 Delta-8 THC is more for medical use than recreational use 2
 Recreational use of Delta-8 THC 2
 Delta-8 THC is better than alcohol 2
 Does not like Delta-8 THC 2

See Supplementary Table S1 for unique responses