Fig. 3.

Selected microphotographs (H&E × 100) of tissues in rats during 28 days repeated dose toxicity study. A: liver (300 mg/kg b.w., female), inflammatory cells and edema; B: heart (100 mg/kg b.w., female), erythrocytosis and edema; C: spleen (100 mg/kg b.w., male), erythrocytosis and congestion; D lung (50 mg/kg b.w., female), connective tissues proliferation and congestion; E: ovaries (100 mg/kg b.w., female), congestion