Table 3.

Absolute and relative organ weights from female rats treated orally with Py-mulin for 28 days

Parameters	0 mg/kg b.w.	50 mg/kg b.w.	100 mg/kg b.w.	300 mg/kg b.w.
Absolute organ weight (g)
Heart	0.75 ± 0.10	0.70 ± 0.10	0.82 ± 0.06	0.81 ± 0.07
Liver	6.89 ± 0.83	7.29 ± 0.90	7.65 ± 1.01	7.88 ± 0.53*
Spleen	0.44 ± 0.08	0.48 ± 0.05	0.42 ± 0.08	0.49 ± 0.07
Lungs	1.04 ± 0.11	1.12 ± 0.13	1.08 ± 0.12	1.05 ± 0.14
Kidneys	1.35 ± 0.14	1.39 ± 0.17	1.41 ± 0.15	1.43 ± 0.17
Thymus	0.35 ± 0.05	0.37 ± 0.06	0.42 ± 0.06	0.41 ± 0.07
Ovaries	0.09 ± 0.02	0.12 ± 0.03	0.11 ± 0.03	0.11 ± 0.04
Organ-to-body weight ratio (%)
Heart	0.39 ± 0.04	0.37 ± 0.04	0.42 ± 0.03	0.41 ± 0.03
Liver	3.61 ± 0.30	3.88 ± 0.33	3.95 ± 0.40	3.97 ± 0.10*
Spleen	0.23 ± 0.03	0.26 ± 0.03	0.22 ± 0.03	0.25 ± 0.03
Lungs	0. 55 ± 0.05	0.59 ± 0.04	0.56 ± 0.04	0.52 ± 0.06
Kidneys	0.71 ± 0.05	0.74 ± 0.06	0.73 ± 0.07	0.72 ± 0.05
Thymus	0.18 ± 0.02	0.20 ± 0.03	0.22 ± 0.02*	0.21 ± 0.03
Ovaries	0.05 ± 0.01	0.06 ± 0.02	0.06 ± 0.02	0.06 ± 0.02

Values are mean ± SD for 10 rats in each group

*Statistically significant difference compared to control (p < 0.05)