Table 5.
Histopathology of rats on day 28 of subacute feeding test of Py-mulin
| Organ | Histopathological characters | 28-day (n = 10) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Control | 50 mg/kg b.w. | 100 mg/kg b.w. | 300 mg/kg b.w. | ||||||
| Female | Male | Female | Male | Female | Male | Female | Male | ||
| Liver | Inflammatory cells | 1/5 | 1/5 | 2/5 | 0/5 | 2/5 | 1/5 | 1/5 | 1/5 |
| Congestion | 1/5 | 0/5 | 0/5 | 0/5 | 1/5 | 1/5 | 1/5 | 2/5 | |
| Edema | 0/5 | 0/5 | 0/5 | 1/5 | 1/5 | 0/5 | 2/5 | 1/5 | |
| Heart | Erythrocytosis | 1/5 | 0/5 | 2/5 | 0/5 | 2/5 | 1/5 | 0/5 | 1/5 |
| Edema | 0/5 | 0/5 | 1/5 | 0/5 | 3/5 | 0/5 | 1/5 | 0/5 | |
| Spleen | Erythrocytosis | 0/5 | 1/5 | 0/5 | 1/5 | 1/5 | 1/5 | 1/5 | 1/5 |
| Congestion | 0/5 | 0/5 | 1/5 | 0/5 | 1/5 | 1/5 | 0/5 | 1/5 | |
| Lungs | Connective tissues proliferation | 1/5 | 1/5 | 1/5 | 2/5 | 1/5 | 0/5 | 2/5 | 2/5 |
| Congestion | 0/5 | 1/5 | 1/5 | 0/5 | 0/5 | 0/5 | 0/5 | 2/5 | |
| Ovaries | Congestion | 0/5 | ˗˗ | 2/5 | ˗˗ | 1/5 | ˗˗ | 1/5 | ˗˗ |