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. 2022 Jan 4;17:2. doi: 10.1186/s13018-021-02746-2

Table.1.

Characteristics of the studies in meta-analysis for the diagnosis of PJI applying Calprotectin

Study Year Country Study design Gender (M/F) Mean age* BMI* Detection method Cutoff values Gold standard
Dariusz Grzelecki et al 2021 Poland P 25/60 68.3 / 65.5 29.3/ 29.9 Immunoturbidimetric Calprotectin Immunoassay (GCal, Gentian, Moss, Norway) 1.5 mg/L ICM (2018)
Jared Warren et al 2021 USA P 57/66 65.4 / 66.9 32.0/ 34.2 Lyfstone Calprotectin Point of Care Test Kit (Lyfstone) 50 mg/L MSIS (2013)
Alexander J Trotter et al 2020 TUK R 37/32 NA NA The Lyfstone calprotectin test (Lyfstone AS, Tromsø, Norway) 14 mg/L ICM (2018)
Marjan Wouthuyzen-Bakker et al 2017 Netherlan-ds P 25/36 60/65 NA The Rapid Calprotectin High Range Quantum Blue Assay (BÜHLMANN laboratories AG) 50 mg/L MSIS (2011)
Marjan Wouthuyzen-Bakker et al 2018 Netherlan-ds P NA NA NA The Rapid Calprotectin High Range Quantum Blue Assay (BÜHLMANN laboratories AG) 50 mg/L MSIS (2011)
Paolo Salari et al 2019 Italy P 36/40 NA NA Calprest NG (Eurospital, Trieste, Italy) 50 mg/L ICM (2018)
Zeyu Zhang et al 2019 China P 20/43 NA NA ELISA (Hycult Biotech, Uden, the Netherlands) 173 ug/ml MSIS (2013)

*The values were given as the number with Non-PJI / PJI, P prospective study, R retrospective study, NA not applicable