Table 3.
The association between perchlorate, iodine and thyroid tumors and nodular goiter by conditional logistic model
Variables | Total cases | NG | PTMC | PTC | ||||
---|---|---|---|---|---|---|---|---|
ORs (%95CI) | P-value | ORs (%95CI) | P-value | ORs (%95CI) | P-value | ORs (%95CI) | P-value | |
N (case/control) | 184/184 | 72/72 | 46/46 | 66/66 | ||||
Perchlorate | 1.041 (1.017, 1.066) | 0.001 | 1.034 (0.994, 1.074) | 0.094 | 1.033 (0.996, 1.072) | 0.084 | 1.058 (1.009, 1.110) | 0.021 |
Iodine | 1.000 (1.000, 1.000) | 0.759 | 1.002 (0.998, 1.005) | 0.303 | 1.000 (0.998, 1.001) | 0.596 | 1.000 (0.999, 1.002) | 0.518 |
Note: Perchlorate and iodine were corrected by urinary specific gravity (USG). Perchlorate, iodine, BMI, smoking, and drinking were included in the model. OR odds ratio, CI confidence interval, NG nodular goiter, PTMC papillary thyroid micro carcinoma, PTC papillary thyroid carcinoma, Total cases including NG, PTMC and PTC