Fig. 10.

Simulation of the ODE system for the Edelstein network using different starting values of $B_{\mathit{tot}}$ and [A]. The system converges to two equilibrium states; a “lower” one at $[A]\approx 1$ and a “higher” one at $[A]\approx 1.75$. If the system starts with a low concentration of A a switch between “low” and “high” equilibrium states happens at smaller concentration of $B_{\mathit{tot}}$. Vice versa, if the system starts with a high concentration of A, the switch between the equilibrium states happens at higher concentrations of $B_{\mathit{tot}}$