Table 3.
Immunohistochemical expression of MMP-3、TIMP-1 in different layers of the articular cartilage of the three groups
| Item | Groups | n | Positive rate (%) | |||
|---|---|---|---|---|---|---|
| Upper layer | Middle layer | Deeper layer | Total layers | |||
| MMP-3 | Control | 21 | 46.50 ± 15.82 | 34.19 ± 16.00 | 15.48 ± 8.54 | 32.06 ± 6.74 |
| KBD | 22 | 63.65 ± 19.78* | 59.83 ± 20.54* | 3.05 ± 20.92* | 51.34 ± 15.07* | |
| OA | 15 | 56.84 ± 20.02 | 57.81 ± 25.58* | 38.68 ± 31.02* | 51.09 ± 14.93* | |
| TIMP-1 | Control | 21 | 45.78 ± 21.27 | 32.91 ± 16.87 | 16.55 ± 11.76 | 31.75 ± 9.87 |
| KBD | 22 | 24.89 ± 22.11* | 20.22 ± 12.53* | 7.06 ± 5.98* | 17.42 ± 8.09* | |
| OA | 15 | 20.38 ± 13.75* | 22.21 ± 11.69* | 7.44 ± 13.77* | 16.67 ± 7.88* | |
* P < 0.05 compared with the control group (t = 2.12–5.37, P<0.05)