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. 2022 Jan 4;14:2. doi: 10.1186/s13098-021-00771-z

Fig. 3.

Fig. 3

Knockdown of LSD1 alleviates renal fibrosis in STZ-induced DN rats. A Masson staining for renal fibrosis in different treated rats, suggesting that shLSD1 rescued STZ-induced renal fibrosis rats. The expression of Fibronectin (B) and α-SMA (C) were determined by IF assay, indicating shLSD1 reversed STZ-induced Fibronectin and α-SMA expression (bar = 100 μm). D The expression of α-SMA, collagen I and collagen IV were determined by western blot. Each group contained 10 rats. **p < 0.01 vs. Sham. ##p < 0.01 vs. STZ + Ad-shLSD1