Table 1.
Comparison of basic information
| Dry eye without AE | Dry eye with AE | Pre-clinical dry eye with AE | ||
|---|---|---|---|---|
| Part 1 | NO. subjects (eyes) | 17 (34) | 17 (34) | 17 (34) |
| Male (eyes): Female (eyes) | 12 (24): 5 (10) | 12 (24): 5 (10) | 12 (24): 5 (10) | |
| Age (years) | 22.0 (21.0, 23.5) | 22.0 (21.0, 24.0) | 21.0 (21.0, 23.3) | |
| OSDI score | 25.0 (19.4, 32.2) | 22.7 (16.0, 32.2) | 16.7 (7.3, 21.3)a | |
| Part 2 | NO. subjects (eyes) | 15 (30) | 15 (30) | 15 (30) |
| Male (eyes): Female (eyes) | 10 (20): 5 (10) | 12 (24): 3 (6) | 12 (24): 3 (6) | |
| Age (years) | 21.0 (21.0, 23.0) | 22.0 (21.0, 23.3) | 21.0 (21.0, 23.0) | |
| OSDI score | 22.9 (20.5, 32.5) | 25.0 (20.0, 45.0) | 13.6 (5.0, 25.0)a |
a There were significant differences compared with the other groups (P < 0.05)
OSDI the ocular surface disease index