Fig. 1.

Clinical course of DSS-induced colitis in mice with a mPGES-1 genetic deletion. A Time course of change in body weight, stool consistency, bleeding score, and total disease activity index (DAI) score of WT and mPGES-1^−/− mice after indicated days of exposure to 1% DSS (n = 17). B On day 7 after the start of exposure to 1% DSS, the length and weight of the colon were measured as an indirect marker of inflammation (n = 3 to 17). Pictures of the colon are representative examples in WT and mPGES-1^−/− mice. *P < 0.05; 2-way ANOVA followed by Tukey multiple comparison test