Figure 1.

Differential gene expression in subjects exposed to DEE (n = 41) compared to DEE unexposed controls (n = 38). Unsupervised hierarchical clustering of 225 genes significantly associated with DEE-exposure status after adjusting for RIN, batch, and smoking status (FDR q < 0.25). Each column represents a sample (n=79) and each row represents each one of the 225 differentially expressed genes. The color bar on the left describes two clusters of gene expression patterns associated with DEE exposure. Genes with increased or decreased expression in DEE exposed individuals are designated as UP or DOWN in Diesel, respectively.