Table 2.
Cardiometabolic profile in patients with acute ischemic strokes regarding statins therapy compared with the controls
| Variables | Controls (n=29) | Statins (n=23) | Nonstatins (n=35) | I | II | III | ANOVA |
|---|---|---|---|---|---|---|---|
| BMI (kg/m2) | 32.69±4.91 | 34.81±6.84 | 35.66±6.28 | NS | NS | NS | 0.14 |
| SBP (mmHg) | 123.48±9.21 | 141.75±10.81 | 145.72±11.68 | 0.001 | 0.001 | NS | 0.001 |
| DBP (mmHg) | 71.89±5.86 | 91.94±7.51 | 95.79±9.73 | 0.001 | 0.001 | NS | 0.001 |
| MAP (mmHg) | 89.09±7.36 | 108.54±9.71 | 112.43±9.74 | 0.001 | 0.001 | NS | 0.001 |
| PP (mmHg) | 51.59±5.84 | 49.81±4.93 | 49.93±4.77 | NS | NS | NS | NS |
| TC (mg/dL) | 177.92±11.65 | 189.56±12.82 | 233.81±15.89 | 0.009 | 0.001 | 0.001 | 0.001 |
| TG (mg/dL) | 132.82±9.41 | 178.92±11.85 | 212.69±18.63 | 0.001 | 0.001 | 0.001 | 0.001 |
| HDL-c (mg/dL) | 49.85±7.67 | 41.91±6.81 | 34.81±4.91 | 0.001 | 0.001 | 0.001 | 0.001 |
| LDL-c (mg/dL) | 101.50±8.47 | 111.90±9.85 | 156.50±17.95 | 0.008 | 0.001 | 0.001 | 0.001 |
| VLDL (mg/dL) | 26.56±6.59 | 35.78±7.54 | 42.53±6.49 | 0.001 | 0.001 | 0.001 | 0.001 |
| Non-HDL-c (mg/dL) | 128.07±8.09 | 147.65±11.76 | 199.00±17.42 | 0.001 | 0.001 | 0.001 | 0.001 |
| AI | 0.066±0.002 | 0.270±0.003 | 0.426±0.003 | 0.001 | 0.001 | 0.03 | 0.001 |
| CCR | 3.56±1.62 | 4.52±1.87 | 6.71±2.81 | NS | 0.001 | 0.001 | 0.001 |
| CVRI | 2.66±1.08 | 4.26±1.99 | 6.11±2.72 | 0.02 | 0.001 | 0.004 | 0.001 |
Data are presented as mean±SD, one-way ANOVA and post hoc test; I: Control versus statins, II: Control versus nonstatins, III: Statins versus nonstatins, NS: Not significant, BMI: Body mass index, SBP: Systolic blood pressure, DBP: Diastolic blood pressure, PP: Pulse pressure, MAP: Mean arterial pressure, TC: Total cholesterol, TG: Triglyceride, HDL: High-density lipoprotein, LDL: Low-density lipoprotein, VLDL: Very low-density lipoprotein, AI: Atherogenic index, CCR: Cardiac risk ratio, CVRI: Cardiovascular risk index