Table 3.

In vitro cytotoxicity of the assessed compounds and sorafenib against normal adult liver epithelial cells (THLE-2 cells).

Comp.	THLE-2 IC50 (µM)a
Sorafenib	27.8 ± 1.74
5	33.7 ± 1.35
8	16.7 ± 0.73
15	34.9 ± 1.86
16	29.7 ± 2.23
17	22.8 ± 1.22
18	28.6 ± 2.1

^aThe mean ± SEM of at least three different experiments is used to calculate all IC₅₀ values.