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. 2021 Dec 29;29(1):99–110. doi: 10.1080/10717544.2021.2021321

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — In vitro biocompatibility of NBs was tested by CCK-8 assay. (a) The original medium was changed to a fresh medium containing PBS (Control), blank NBs, or SCR siRNA-NBs (at siRNA-NBs volume 10 µL/well or siRNA 6 pmol/well). (b) The original medium was changed to a fresh medium containing PBS (Control), different concentrations of blank NBs, or SCR siRNA-NBs (at 1.0 × 10⁶, 5.0 × 10⁶, 1.0 × 10⁷, 5.0 × 10⁷, 1.0 × 10⁸, and 5.0 × 10⁸ bubbles/mL). *p < .05, compared with Control.