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. Author manuscript; available in PMC: 2022 Jan 4.
Published in final edited form as: Cytotherapy. 2015 May;17(5):621–632. doi: 10.1016/j.jcyt.2015.03.611

Figure 1.

Figure 1.

Expansion kinetics and effector functions of differentially expanded NK cells. (A) Automated EBV-LCL–based expansion of NK cells (circles) in comparison to manual NK cell expansion in T flasks with (squares) or without (triangles) EBV-LCL. NK cell numbers displayed for manual expansion are theoretical and were calculated by the NK cell fold expansion obtained in T flasks multiplied by the same starting NK cell number as in the automated approach. (B) Differentially expanded NK cells were tested for their reactivity by staining for CD107a, IFN-γ and TNF-α before (white bars) and after (gray bars) stimulation with K562 target cells. NK cells from 10 (A) or six (B) donors were analyzed; displayed are mean values and P values for paired Student’s t-test, with P < 0.05 considered significant.