Table 1.
Characteristic | N | % |
---|---|---|
| ||
Age (years) | ||
Mean (± standard deviation) | 63.9 (± 10.8) | |
Median | 63.7 | |
Range | 34 to 91 | |
| ||
BMI [kg/m 2 ] | ||
Mean (± standard deviation) | 28.2 (± 5.3) | |
Median | 27.6 | |
Range | 15.4 to 56.0 | |
| ||
Comorbidities | ||
Diabetes mellitus | 85 | 21.6 |
Arterial hypertension | 215 | 54.7 |
Smoker | 90 | 22.9 |
| ||
Breast side | ||
Right | 213 | 54.2 |
Left | 177 | 45.0 |
Bilateral | 3 | 0.8 |
| ||
Histology * | ||
Ductal carcinoma in situ | 20 | 5.1 |
Invasive carcinoma | 324 | 81.8 |
Invasive lobular carcinoma | 20 | 5.1 |
Others | 32 | 8.1 |
| ||
Estrogen receptor positive* | 349 | 88.1 |
| ||
Progesterone receptor positive* | 306 | 77.3 |
| ||
HER-2 Positive* | 22 | 5.6 |
| ||
Luminal A or B “like”* | 338 | 85.4 |
| ||
Triple negative* | 36 | 9.1 |
| ||
Clinical stage (AJCC 7 th ed) * | ||
0 | 23 | 5.8 |
I–IIA | 235 | 59.4 |
IIB–IIIB | 138 | 34.8 |
| ||
Surgery * | ||
Conservative | 375 | 94.7 |
Nipple-sparing mastectomy | 4 | 1.0 |
Modified radical mastectomy | 17 | 4.3 |
Breast reconstruction | 6 | 1.5 |
| ||
Pathological stage (AJCC 7 th ed) * | ||
0 | 22 | 5.6 |
I–IIA | 339 | 85.6 |
IIB–IIIB | 35 | 8.8 |
| ||
pT stage * | ||
pTis | 22 | 5.6 |
pT0–T2 | 367 | 92.6 |
pT3–T4 | 7 | 1.8 |
| ||
pN stage * | ||
pN0 | 331 | 83.6 |
pN1mi | 26 | 6.6 |
pN1a | 34 | 8.6 |
pN2a | 4 | 1.0 |
pN3a | 1 | 0.2 |
| ||
Chemotherapy | ||
None | 228 | 58.0 |
Neoadjuvant | 16 | 4.1 |
Adjuvant | 149 | 37.9 |
| ||
Hormone therapy | 344 | 87.5 |
| ||
Radiotherapy fractionation | ||
15 fractions | 161 | 40.6 |
16 fractions | 147 | 37.1 |
17 fractions | 88 | 22.3 |
| ||
Additional radiotherapy fields * | ||
Supraclavicular/axillary | 13 | 3.3 |
Internal mammary | 1 | 0.3 |
Boost | 110 | 27.8 |
| ||
Tangential fields separation [cm] * | ||
Mean (± standard deviation) | 18.0 (± 2.9) | |
Median | 17.8 | |
Range | 8.5 to 27.0 | |
| ||
PTV [cc] * | ||
Mean (± standard deviation) | 915.6 (± 368.5) | |
Median | 868.8 | |
Range | 211.9 to 2402.8 |
N — number; BMI — body mass index; PTV — planning target volume;
Data regarding the number of treated breasts