Table 2.
Bivariate COX regression
| Bivariate* | LC | ||
|---|---|---|---|
| Variable | Category | HR (95% CI) | p-value |
|
| |||
| Age | 1.03 (0.98, 1.07) | 0.216 | |
|
| |||
| Sex | |||
|
| |||
| Male | Reference | ||
|
| |||
| Female | 0.95 (0.21, 4.27) | 0.952 | |
|
| |||
| T | |||
|
| |||
| 1 | Reference | ||
|
| |||
| 2 | 1.42 (0.24, 8.31) | 0.700 | |
|
| |||
| > 2 | 1.37 (0.12, 15.51) | 0.800 | |
|
| |||
| Localization | |||
|
| |||
| Superficial | Reference | ||
|
| |||
| Superficial + deep | 0.61 (0.07, 5.07) | 0.647 | |
|
| |||
| Histology | |||
|
| |||
| Epidermoid | Reference | ||
|
| |||
| Others | 0.36 (0.08, 1.62) | 0.185 | |
| Dose RT | |||
|
| |||
| 1.04 (0.92, 1.17) | 0.505 | ||
|
| |||
| ≤ 65 | Reference | ||
|
| |||
| > 65 | 2.45 (0.54, 11.20) | 0.248 | |
|
| |||
| Indication RT | |||
|
| |||
| G3 | Reference | 0.468 | |
|
| |||
| R1 | 0.73 (0.12, 4.52) | 0.738 | |
|
| |||
| G3 + R1 | 2.59 (0.36, 18.77) | 0.348 | |
|
| |||
| Indication RT | |||
|
| |||
| Not G3 | Reference | ||
|
| |||
| G3 | 3.19 (0.61, 16.6) | 0.168 | |
|
| |||
| Type of surgery | |||
|
| |||
| Superficial parotidectomy | Reference | ||
|
| |||
| Total parotidectomy | 2.20 (0.40, 12.1) | 0.362 | |
|
| |||
| Time from surgery to RT | |||
|
| |||
| 1.00 (0.999, 1.001) | 0.788 | ||
|
| |||
| ≤ 60 | Reference | ||
|
| |||
| > 60 | 2.17 (0.48, 9.71) | 0.311 | |
LC — local control; HR — hazard ratio; CI — confidence interval; RT — radiotherapy.
*
There is no variable significantly associated with time to relapse-free.
There are some factors with a HR greater than 2 (highlighted in red) that could indicate a certain trend