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. 2021 Dec 10;18(12):e1003877. doi: 10.1371/journal.pmed.1003877

Table 4. Seroprevalence of IgG antibodies against SARS-CoV-2 in the general population by vaccination status, June–July 2021.

Characteristic Unvaccinated Vaccinated with 1 dose Vaccinated with 2 doses
Number tested Number positive (anti-N and/or anti-S1-RBD antibodies) Cluster- and test-adjusted seroprevalence, percent (95% CI) Number tested Number positive (anti-N and/or anti-S1-RBD antibodies) Cluster- and test-adjusted seroprevalence, percent (95% CI) Number tested Number positive (anti-N and/or anti-S1-RBD antibodies) Cluster- and test-adjusted seroprevalence, percent (95% CI)
Age
18–44 years 8,986 5,381 60.8 (59.2–62.3) 2,426 1,896 80.4 (78.2–82.4) 1,096 958 89.1 (86.7–91.3)
45–60 years 2,701 1,778 67.0 (64.8–69.1) 1,830 1,521 85.5 (83.4–87.3) 1,013 917 91.9 (89.7–93.6)
>60 years 912 599 67.0 (63.6–70.4) 782 599 78.9 (75.4–82.0) 522 456 88.7 (85.4–91.5)
Gender
Male 10,040 5,962 59.6 (57.8–61.4) 2,598 2,050 81.0 (79.0–82.9) 1,136 999 89.4 (87.1–91.5)
Female 11,223 6,998 64.9 (63.2–66.4) 2,436 1,962 83.1 (81.1–84.9) 1,493 1,330 90.7 (88.6–92.3)
Other 26 17 74.0 (44.9–90.8) 4 4 2 2
Area of residence
Rural 3,702 2,280 62.1 (60.5–63.7) 1,046 846 81.1 (79.2–82.9) 515 459 90.1 (88.0–91.7)
Urban non-slum 16,236 9,832 63.6 (60.2–66.8) 3,603 2,840 83.2 (79.8–86.1) 1,941 1,716 90.4 (86.9–93.0)
Urban slum 1,351 865 64.6 (59.0–69.8) 389 330 87.1 (82.1–90.9) 175 156 90.9 (84.7–94.7)
Previous COVID-19 test result
Reported positive for COVID-19 487 402 86.0 (82.2–89.1) 145 134 94.7 (90.1–97.2) 150 138 93.8 (88.6–96.7)
Reported negative for COVID-19 1,732 1,051 62.9 (59.7–66.1) 962 739 80.1 (76.9–83.0) 724 634 89.4 (86.5–91.8)
Don’t know 119 58 60.2 (46.5–72.5) 36 28 84.1 (67.5–93.1) 16 11 66.7 (37.4–87.0)
Vaccine type
Covaxin 385 302 80.8 (75.7–85.0) 202 171 86.3 (80.4–90.8)
Covishield 4,565 3,636 82.0 (80.3–83.6) 2,380 2,115 90.3 (88.5–91.8)
Individuals with optimal interval between vaccination and blood sample collection (21 days or more after first dose, 7 days or more after second dose)
Covaxin 223 186 84.3 (78.4–88.9) 201 170 86.3 (80.3–90.7)
Covishield 3,045 2,535 84.8 (83.1–86.5) 2,380 2,115 90.3 (88.5–91.8)

N, nucleocapsid protein.