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. 2022 Jan 4;98(1):e40–e50. doi: 10.1212/WNL.0000000000012952

Figure 3. PD Diary “Off” Time and “On” Times at Baseline and Months 12, 24, and 36.

Figure 3

Data shown are mean hours normalized to a 16-hour waking day. Change from baseline (CFB) at 36 months is reported to the right of each panel. PD diary “off” time and good “on” time (sum of “on” time with no dyskinesia and “on” time with nontroublesome dyskinesia [NTD]) were stable or improved from baseline throughout the trial. In a sensitivity analysis that excluded the participant in cohort 1 who underwent deep brain stimulation, “off” time and good “on” time (mean ± SEM) at month 36 were 3.4 ± 1.5 hours and 12.3 ± 1.6 hours, respectively. TD = troublesome dyskinesia.