Table 1.

Initial clinical characteristics of the patients of two groups

Clinical features	With initial etoposide	Without initial etoposide	p valve	Total
	(n = 52)	(n = 14)		(n = 66)
Age, years
Median	48	44.5	0.881	48
Range	[15, 76]	[29, 65]		[15, 76]
Gender			0.544
Male (n)	32	7		39
Female (n)	20	7		27
Lymphoma classification			0.635
B cell	26	6		32
T/NK cell	26	8		34
Fever (T > 38.5°C)	52 (100%)	14 (100%)		66 (100%)
Splenomegaly (n)	38 (73.1%)	11 (78.6%)	1.00	49 (74.2%)
Haemophagocytosis (n)	45 (86.5%)	11 (78.6%)	0.431	56 (84.8%)
WBC (*109/L)	2.25 [0.06, 17.00]	3.25 [0.4, 8.75]	0.165	2.55 [0.06, 17.00]
HGB (g/L)	90.05 ± 21.84	81.71 ± 15.11	0.184	88.29 ± 20.781
PLT (*109/L)	47.5 [3, 344]	61.5 [9, 392]	0.252	50.5 [3, 392]
ALT (U/L)	52.5 [7.0, 798.0]	41.5 [13, 235]	0.753	51.5 [7.0, 798.0]
AST (U/L)	56.4 [3.3, 520.2]	43.9 [14.3, 990.0]	0.869	55.2 [3.3, 990.0]
LDH	556 [137, 4581]	990 [76, 1986]	0.569	537 [76, 4581]
Total bilirubin (µmol/L)	24.77 [6.29, 348.15]	20.70 [6.50, 213.58]	0.718	22.9 [6.29, 348.15]
ALB	28.5 [19.2, 44.0]	28.7 [20.1, 34.8]	0.389	28.2 ± 5.27
Cr (umol/L)	59.7 [35.5, 125]	64.4 [37.7, 272.3]	0.725	60 [35.5, 272.3]
TG (mmol/L)	2.45 ± 1.22	2.95 ± 1.49	0.215	2.30 [0.69, 5.68]
Fbg (g/L)	1.76 [0.16, 8.47]	3.7 [0.73, 8.68]	0.017	1.96 [0.16, 8.68]
Ferritin (ng/mL)	2307.5 [204.3, 75000]	2574 [557.3, 45487]	0.734	2447 [204.3, 75000]
sCD25 (pg/mL)	36605 [661, 44000]	34749 [3827, 44000]	0.903	36517 [661, 44000]
IPI scores	3.00 ± 0.913	3.29 ± 0.994	0.315	3.06 ± 0.931
EBV-positive	23 (44.2%)	6 (42.8%)	0.927	29 (43.9%)
Corticosteroid contained	51 (98.1%)	13 (92.9%)	0.382	64 (97.0%)
Outcome
Death	28 (53.8%)	12 (85.7%)	0.030	40 (60.6%)
Survival	25.8 w [95%CI (13.2, 38.5)]	7.6 w [95% (0, 19.8)]	0.048	23.8 w [95%CI (15.5, 32.2)]

The valve was expressed as median [range] or mean±standard deviation.