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. 2021 Dec 25;14(1):264–269. doi: 10.1080/19420889.2021.2017099

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — ciEVs and cyEVs have unique biomarkers

(a) EV isolation from ciliated (wild-type; ciEVs) and non-ciliated (IFT88; cyEVs) cells reveals unique biomarkers. (b) The volcano plot shows the top five distinctive identified biomarkers based on their pvalue and fold-change for cyEVs (blue color) and ciEVs (red color). The dot blot analyses show the expression of the top cyEV and ciEV biomarkers (CD166 and POR, respectively) in isolated EVs. HSP70 and Golgi-97 were used as positive and negative controls for extracellular vesicles, respectively.