Table 1.
List of the antibodies used in the study
| mAb name | Constant region |
Variable region |
Mutations from germline | |
|---|---|---|---|---|
| CH | CL | Fv | ||
| IgG1-A | IgG1 | Kappa | A | None |
| IgG1EN-A | IgG1EN | Kappa | A | L234A, L235E, G237A, A330S, P331S |
| IgG2-A | IgG2 | Kappa | A | None |
| IgG4-A | IgG4PAA | Kappa | A | S228P, F234A, L235A |
| IgG1-B | IgG1 | Kappa | B | None |
| IgG1EN-B | IgG1EN | Kappa | B | L234A, L235E, G237A, A330S, P331S |
| IgG2-B | IgG2 | Kappa | B | None |
| IgG4-B | IgG4PAA | Kappa | B | S228P, F234A, L235A |
| IgG1-C | IgG1 | Kappa | C | None |
| IgG1EN-C | IgG1EN | Kappa | C | L234A, L235E, G237A, A330S, P331S |
| IgG2-C | IgG2 | Kappa | C | None |
| IgG4-C | IgG4PAA | Kappa | C | S228P, F234A, L235A |