ADCC |
Antibody-dependent cell-mediated cytotoxicity |
ADCP |
Antibody dependent phagocytosis |
CDC |
Complement dependent cytotoxicity |
CDR |
Complementarity-determining region |
cIEF |
Capillary isoelectric focusing |
DSC |
Differential scanning calorimetry |
Fab |
Antigen-binding fragment |
Fc |
Crystallizable fragment |
FcγR |
Fc gamma receptor |
HC |
Heavy chain |
HIC |
Hydrophobic-Interaction-Chromatography |
IgG1EN |
Human IgG1 with mutations consisting of L234A, L235E, G237A, A330S, and P331S |
IgG4PAA |
Human IgG4 variant with mutations consisting of S228P, L234A, and L235A |
LC |
Light chain |
mAb |
Monoclonal antibody |
NTU |
Nephelometric Turbidity Units |
pI |
Isoelectric point |
SAP |
Spatial aggregation potential |
SCM |
Surface charge map |
SEC |
Size-exclusion-chromatography |