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. 2021 Dec 28;2021:4508533. doi: 10.1155/2021/4508533

Table 2.

Changes in the contents of 18 elements in rats with cerebral ischemia (n = 6, μg/kg).

Element Group Absorption Distribution Excretion
Hepatic venous blood Abdominal aortic blood Brain Kidney Liver Urine Hair Feces
Li Sham 1.799 ± 1.469 0.573 ± 0.240 0.021 ± 0.027 0.025 ± 0.035 — 0.298 ± 0.082 0.603 ± 0.128 0.9705 ± 0.03541
QSW + MCAO 0.846 ± 0.119 0.827 ± 0.227 0.121 ± 0.053∗ 0.261 ± 0.148 0.112 ± 0.113 2.921 ± 1.687∗ 1.658 ± 0.417 22.74 ± 2.601∗
Be Sham 0.041 ± 0.070 0.007 ± 0.008 0.021 ± 0.028 0.006 ± 0.008 0.006 ± 0.008 0.006 ± 0.007 0.002 ± 0.031 0.0447 ± 0.0216
QSW + MCAO 0.015 ± 0.018 0.002 ± 0.006 — 0.002 ± 0.004 0.026 ± 0.058 0.005 ± 0.007 105.5 ± 211.1 87.93 ± 0.660
Sc Sham 0.018 ± 0.024 0.002 ± 0.002 0.016 ± 0.013 0.002 ± 0.002 0.021 ± 0.028 0.001 ± 0.002 0.019 ± 0.007 0.0434 ± 0.0171
QSW + MCAO 0.001 ± 0.001 0.001 ± 0.001 0.006 ± 0.005 0.008 ± 0.006 0.012 ± 0.007 0.004 ± 0.004 40.63 ± 81.18 95.76 ± 14.48
V Sham 0.430 ± 0.328 0.029 ± 0.005 0.441 ± 0.072 0.736 ± 0.486 0.845 ± 0.664 0.023 ± 0.004 0.319 ± 0.033 11.28 ± 0.532
QSW + MCAO 0.070 ± 0.087∗ 0.045 ± 0.011∗ 0.132 ± 0.015 1.057 ± 0.341 0.524 ± 0.199 0.068 ± 0.033∗ 11.16 ± 21.32 35.49 ± 23.53∗
Cr Sham 9.508 ± 6.316 7.412 ± 1.188 192.2 ± 26.37 9.153 ± 0.409 25.71 ± 18.07 6.913 ± 0.679 21.61 ± 1.308 0.912 ± 0.6191
QSW + MCAO 11.09 ± 0.701 9.344 ± 0.713∗ 9.889 ± 1.242∗ 17.99 ± 16.83 36.01 ± 19.77 7.268 ± 0.506 25.31 ± 21.61 12.740 ± 8.081∗
Mn Sham 1.166 ± 1.643 0.027 ± 0.055 12.38 ± 3.375 30.41 ± 12.66 29.13 ± 0.699 0.038 ± 0.075 7.336 ± 0.793 330.8 ± 167.5
QSW + MCAO 2.246 ± 5.481 0.009 ± 0.022 10.08 ± 1.656 262.3 ± 52.30 80.75 ± 10.24∗ 0.241 ± 0.248 40.16 ± 30.79 50480 ± 27940∗
Co Sham 0.044 ± 0.023 0.013 ± 0.006 0.493 ± 0.272 1.481 ± 1.650 1.395 ± 1.362 0.135 ± 0.177 0.115 ± 0.016 0.2862 ± 0.1663
QSW + MCAO 0.047 ± 0.053 0.026 ± 0.004∗ 0.089 ± 0.011 1.783 ± 0.303 0.589 ± 0.116 0.139 ± 0.074 0.656 ± 0.748 42.86 ± 9.576∗
Ni Sham 41.84 ± 21.08 31.91 ± 4.188 977.7 ± 616.2 36.22 ± 0.577 38.97 ± 0.064 28.98 ± 2.942 77.52 ± 12.03 30.60 ± 13.27
QSW + MCAO 46.04 ± 2.302 37.96 ± 3.100∗ 37.06 ± 4.362 36.94 ± 1.428 36.74 ± 1.222∗ 28.79 ± 2.422 38.78 ± 0.989∗ 1460 ± 1977
Cu Sham 66.99 ± 47.98 54.53 ± 48.46 147.2 ± 17.60 196.4 ± 2.363 206.3 ± 24.72 59.11 ± 39.59 147.6 ± 5.267 12.68 ± 62.45
QSW + MCAO 41.11 ± 41.22 46.93 ± 44.93 140.3 ± 9.885 255.4 ± 48.35 220.1 ± 13.79 30.79 ± 44.10 269.9 ± 105.1 2325 ± 191.3∗
As Sham 368.9 ± 269.3 209.02 ± 74.28 3.215 ± 1.613 19.27 ± 6.584 19.73 ± 4.745 1.541 ± 0.038 1.792 ± 0.352 0.2964 ± 0.1596
QSW + MCAO 101.2 ± 3.592 157.4 ± 25.59 2.042 ± 0.275 19.59 ± 4.862 23.95 ± 5.165 4.224 ± 0.464 55.86 ± 104.4 81.92 ± 9.358∗
Sr Sham 3.028 ± 4.483 0.026 ± 0.052 0.658 ± 0.299 0.262 ± 0.371 0.598 ± 0.042 0.581 ± 0.082 2.085 ± 0.1211 18.63 ± 7.826
QSW + MCAO 1.156 ± 2.427 0.451 ± 0.132∗ 0.516 ± 0.144 1.055 ± 0.492 0.265 ± 0.494 5.612 ± 3.481∗ 6.876 ± 5.843 3091 ± 1423∗
Ag Sham 0.116 ± 0.053 0.011 ± 0.014 0.854 ± 1.242 0.016 ± 0.001 0.091 ± 0.079 — 0.632 ± 0.979 0.1119 ± 0.01198
QSW + MCAO 0.130 ± 0.150 0.020 ± 0.023 0.142 ± 0.079 0.195 ± 0.097∗ 0.147 ± 0.091 0.058 ± 0.036 5.781 ± 10.01 151.30 ± 69.56∗
Cd Sham 0.030 ± 0.034 — 0.064 ± 0.031 0.229 ± 0.086 0.232 ± 0.095 — 0.025 ± 0.008 0.0107 ± 0.0559
QSW + MCAO 0.022 ± 0.038 0.001 ± 0.002 0.003 ± 0.004∗ 0.153 ± 0.088 0.152 ± 0.076 0.005 ± 0.004 18.79 ± 37.49 2063 ± 203.9∗
Cs Sham 0.119 ± 0.076 0.051 ± 0.019 0.269 ± 0.047 0.435 ± 0.007 0.509 ± 0.105 0.069 ± 0.001 0.056 ± 0.005 0.0156 ± 0.0056
QSW + MCAO 0.054 ± 0.010 0.078 ± 0.009 0.296 ± 0.068 0.908 ± 0.167∗ 0.782 ± 0.097 0.233 ± 0.114∗ 15.02 ± 29.69 242.5 ± 113.5∗
Ba Sham 3.597 ± 3.848 1.477 ± 1.124 0.512 ± 0.465 0.235 ± 0.332 0.453 ± 0.634 — 2.103 ± 0.291 4.731 ± 1.736
QSW + MCAO 2.816 ± 5.429 0.352 ± 0.233 0.580 ± 1.037 0.662 ± 0.559 0.257 ± 0.500 — 6.439 ± 6.517 10360 ± 8227∗
Pb Sham 0.925 ± 1.059 — — — 0.161 ± 0.028 — 0.830 ± 0.362 0.2564 ± 0.1205
QSW + MCAO 0.477 ± 1.168 — 0.122 ± 0.176 1.216 ± 0.951 2.672 ± 2.554 0.204 ± 0.378 6.747 ± 3.947 198.40 ± 154.50∗
Au Sham 0.024 ± 0.027 — 0.003 ± 0.006 0.013 ± 0.018 0.007 ± 0.009 — — 0.0131 ± 0.0204
QSW + MCAO 0.010 ± 0.017 0.004 ± 0.006 0.020 ± 0.029 0.351 ± 0.372 0.179 ± 0.207 0.022 ± 0.043 3.171 ± 3.106 12.01 ± 23.46
Hg Sham 0.630 ± 0.394 0.429 ± 0.174 0.283 ± 0.099 0.468 ± 0.423 0.592 ± 0.445 0.050 ± 0.012 0.624 ± 0.103 0.0117 ± 0.005
QSW + MCAO 0.460 ± 0.226 0.359 ± 0.032 0.358 ± 0.112 2.998 ± 1.231 0.606 ± 0.083 0.794 ± 0.446∗ 9.332 ± 2.793∗ 118.50 ± 84.31∗

The symbol “—” means not detected or lower than the detection limit; compared with the Sham group, ∗p < 0.05.