Table 2.

Metabolic correlates of hyposmia in post-COVID (A) and de novo PD patients (B)

Cluster extent	Cluster level	Cortical region	Peak level		Talairach coordinates		Cortical region	BA
	Corrected p value		Maximum z-score
A
420	0.006
		L-frontal	4.7	− 6	16	− 24	Rectal gyrus	11
		R-frontal	4.5	2	24	− 18	Medial frontal gyrus	25
		R-limbic	4.09	10	6	36	Cingulate gyrus	24
		R-limbic	3.75	8	18	36	Cingulate gyrus	32
		R-temporal	3.65	58	8	− 20	Middle temporal gyrus	21
B
1964	0.001
		R-occipital	6.20	22	− 92	28	Cuneus	19
		R-parietal	5.30	42	− 60	32	Angular gyrus	39
		L-parietal	4.90	− 42	− 78	40	Precuneus	19
155	0.034	L-occipital	4.44	− 40	− 84	28	Superior occipital gyrus	19
		L-occipital	4.27	− 20	− 84	16	Middle occipital gyrus	18

Uncorrected p < 0.001 at peak level and p < 0.05 FWE-corrected at cluster level were accepted as statistically significant. In the “cluster level” section on the left, the corrected p value and the brain lobe with hypometabolism are reported. In the “peak level” section on the right, the z-score and peak coordinates, the corresponding cortical region, and Brodmann area (BA) are reported

L, left; R, right