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. 2022 Jan 5;26(5):2967–2980. doi: 10.1007/s11030-021-10375-4

Scheme 11.

Scheme 11

Synthesis of 3′,4′-diaryl-4′H-spiro[indoline-3,5′-[1′,2′,4′]oxadiazol]-2-ones (66) via DMAP-catalyzed domino reaction. Conditions: (i) EtOH, rt, 3 h, DMAP (10 mol%), rt, 3 h