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. 2021 Dec 27;13(12):2052–2070. doi: 10.4254/wjh.v13.i12.2052

Table 1.

Atherogenic ratios, inflammation and endothelial dysfunction markers in a nutritional model of steatohepatitis

Variable
Control (n = 10)
Intervention (n = 10)
P value
AC 0.6 (0.2–0.9) 2.5 (1.5–3.4) < 0.001a
CRI-I 1.6 (± 0.4) 3.5 (± 1.1) < 0.001a
CRI-II 0.3 (± 0.1) 0.8 (± 0.2) < 0.001a
IL-1β (pg/mL) 367.7 (± 31.2) 465.9 (± 52.7) 0.001a
MCP-1 (ng/mL) 2.7 (± 0.6) 3.8 (± 0.9) 0.005a
TIMP-1 (ng/mL) 7.1 (± 1.4) 12.4 (± 2.3) < 0.001a
PAI-1 (ng/mL) 0.11 (± 0.05) 0.17 (± 0.06) 0.037a

Data are means ± standard deviation or medians (25th-75th percentiles).

a

P ≤ 0.05 was considered statistically significant.

AC: Atherogenic coefficient; CRI: Castelli’s risk index; IL: Interleukin; MCP: Monocyte chemoattractant protein; PAI: Plasminogen activator inhibitor; TIMP: Tissue inhibitor of metalloproteinase.